Rapid determination of 103 common veterinary drug residues in milk and dairy products by ultra performance liquid chromatography tandem mass spectrometry
机构：[1]Fourth Hospital of Hebei Medical University, Shijiazhuang, China,河北医科大学第四医院[2]Technology Center of Shijiazhuang Customs District, Shijiazhuang, China,[3]Hebei Food Inspection and Research Institute, Shijiazhuang, China,[4]Hebei Key Laboratory of Forensic Medicine, College of Forensic Medicine, Hebei Medical University, Shijiazhuang, China
A multi-residue method has been developed for the identification and quantification of 103 common veterinary drug residues in milk and dairy Products. This method was based on QuEChERS with dispersive solid-phase where C18 sorbent and anhydrous sodium sulfate were used to sample purification. After evaporation and reconstitution, the samples were analyzed by ultra-performance liquid chromatography-tandem mass spectrometry. The mean recovery results were all higher than 60% except ampicillin, pipemidic acid, enoxacin, and estriol, and the relative standard deviation was < 20.0%. The limit of quantification ranged between 0.1 and 5 mu g/kg for milk and between 0.5 and 25 mu g/kg for milk powder. It was successfully used to detect residues of veterinary drug in real samples. This study proposes a simple and fast analytical method for monitoring multi-class veterinary drug residues to ensure food safety.
基金：
Science and Technology
project of Hebei Province (21475501D) and Science
and Technology project of general Administration of
China (2019HK112).
第一作者机构：[1]Fourth Hospital of Hebei Medical University, Shijiazhuang, China,
通讯作者：
通讯机构：[3]Hebei Food Inspection and Research Institute, Shijiazhuang, China,[4]Hebei Key Laboratory of Forensic Medicine, College of Forensic Medicine, Hebei Medical University, Shijiazhuang, China
推荐引用方式(GB/T 7714)：
Guo Xiujuan,Tian Hao,Yang Fan,et al.Rapid determination of 103 common veterinary drug residues in milk and dairy products by ultra performance liquid chromatography tandem mass spectrometry[J].FRONTIERS IN NUTRITION.2022,9:doi:10.3389/fnut.2022.879518.
APA：
Guo, Xiujuan,Tian, Hao,Yang, Fan,Fan, Sufang,Zhang, Jingwen...&Zhang, Yan.(2022).Rapid determination of 103 common veterinary drug residues in milk and dairy products by ultra performance liquid chromatography tandem mass spectrometry.FRONTIERS IN NUTRITION,9,
MLA：
Guo, Xiujuan,et al."Rapid determination of 103 common veterinary drug residues in milk and dairy products by ultra performance liquid chromatography tandem mass spectrometry".FRONTIERS IN NUTRITION 9.(2022)
