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The dual role of ferroptosis in anthracycline-based chemotherapy includes reducing resistance and increasing toxicity

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收录情况： ◇ SCIE

作者：
Zhao Jiazheng[1] * ; Zhang Ning[2] ; Ma Xiaowei[3] ; Li Ming[4] ; Feng Helin[3] ;
机构： [1]Department of Orthopedics, The Fourth Hospital of Hebei Medical University, 12 Health Road, Shijiazhuang, Hebei, 050011, China. [2]Department of Cardiology, The Fourth Hospital of Hebei Medical University, 12 Health Road, Shijiazhuang, Hebei, 050011, China. [3]Departments of Orthopedics, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Nanli, Panjiayuan, Chaoyang District, Beijing, 100021, China. [4]Department of Orthopedics, The Second Hospital of Hebei Medical University, 215 Heping Road, Shijia-zhuang, Hebei, China.
出处：
DOI： 10.1038/s41420-023-01483-1

摘要：
In conjunction with previous studies, we have noted that ferroptosis, as an emerging mode of regulated cell death (RCD), is intimately related to anthracycline pharmacotherapy. Not only does ferroptosis significantly modulate tumour resistance and drug toxicity, which are core links of the relevant chemotherapeutic process, but it also appears to play a conflicting role that has yet to be appreciated. By targeting the dual role of ferroptosis in anthracycline-based chemotherapy, this review aims to focus on the latest findings at this stage, identify the potential associations and provide novel perspectives for subsequent research directions and therapeutic strategies.© 2023. The Author(s).

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外文
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中科院分区：
出版当年[2023]版：
大类 | 2 区 生物学
小类 | 2 区 细胞生物学
最新[2025]版：
大类 | 2 区 生物学
小类 | 2 区 细胞生物学
JCR分区：
出版当年[2023]版：
Q1 CELL BIOLOGY
最新[2023]版：
Q1 CELL BIOLOGY

影响因子： 最新[2023版] 最新五年平均 出版当年[2023版] 出版当年五年平均 出版前一年[2022版]

第一作者：
第一作者机构： [1]Department of Orthopedics, The Fourth Hospital of Hebei Medical University, 12 Health Road, Shijiazhuang, Hebei, 050011, China.
通讯作者：
推荐引用方式(GB/T 7714)：
Zhao Jiazheng,Zhang Ning,Ma Xiaowei,et al.The dual role of ferroptosis in anthracycline-based chemotherapy includes reducing resistance and increasing toxicity[J].CELL DEATH DISCOVERY.2023,9(1):doi:10.1038/s41420-023-01483-1.
APA：
Zhao Jiazheng,Zhang Ning,Ma Xiaowei,Li Ming&Feng Helin.(2023).The dual role of ferroptosis in anthracycline-based chemotherapy includes reducing resistance and increasing toxicity.CELL DEATH DISCOVERY,9,(1)
MLA：
Zhao Jiazheng,et al."The dual role of ferroptosis in anthracycline-based chemotherapy includes reducing resistance and increasing toxicity".CELL DEATH DISCOVERY 9..1(2023)

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