To the Editor: The link between air pollution and autoimmune diseases is gaining attention in the current field of environmental health research. A recent study based on data from the UK Biobank examined the relationship between long-term exposure to air pollution and the risk of developing systemic lupus erythematosus (SLE). The study found that long-term exposure to air pollution was significantly associated with the development of SLE, providing new insights into the role of environmental factors in the pathogenesis of SLE. The findings highlight the need for stricter air quality standards to reduce potential health risks.1 In addition, the study lays the groundwork for further research into the relationship between air pollution and other autoimmune diseases and calls for more interdisciplinary research to understand the complex pathomechanisms. Although this study makes an important contribution to understanding the role of environmental factors in the development of SLE, other methodologic limitations not mentioned in the text need to be carefully considered when interpreting the results.