Background: Residual cancer burden significantly impacts the efficacy of neoadjuvant chemotherapy (NAC) in breast cancer.Post-NAC changes in the tumor bed complicate the pathological evaluation of surgical specimens. Beyond the binary classification of pathological complete response (pCR), existing residual cancer burden (RCB) and post-NAC systems often overlook the histological patterns of residual tumors in non-pCR cases. Therefore,
additional risk stratification measures are crucial for breast cancer
patients with residual disease following NAC. This study aims to assess oncologic outcomes in a contemporary cohort receiving NAC and to evaluate the prognostic significance of histological patterns of residual tumors.
第一作者机构：[1]Hebei Med Univ, Hosp 4, Shijiazhuang, Peoples R China
推荐引用方式(GB/T 7714)：
Ding Yan,He Xiaoqing,Li Jinze,et al.Residual Tumor Histology after Neoadjuvant Chemotherapy: A Novel Approach to Risk Stratification in Breast Cancer[J].LABORATORY INVESTIGATION.2025,105(3):doi:10.1016/j.labinv.2024.102360.
APA：
Ding, Yan,He, Xiaoqing,Li, Jinze,Luo, Yuqing&Liu, Yueping.(2025).Residual Tumor Histology after Neoadjuvant Chemotherapy: A Novel Approach to Risk Stratification in Breast Cancer.LABORATORY INVESTIGATION,105,(3)
MLA：
Ding, Yan,et al."Residual Tumor Histology after Neoadjuvant Chemotherapy: A Novel Approach to Risk Stratification in Breast Cancer".LABORATORY INVESTIGATION 105..3(2025)
