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Impact of Healthcare-Associated Infections on Length of Stay: A Study in 68 Hospitals in China

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机构: [1]Peking University First Hospital, Beijing 100034, China [2]Shandong Provincial Hospital, Jinan 250021, China [3]Guangdong General Hospital, Guangzhou 510008, China [4] The First Affiliated Hospital of Anhui Medical University, Hefei 230022, China [5]The First Hospital, Shanxi Medical University, Taiyuan 030001, China [6]Xiangya Hospital, Central SouthUniversity, Changsha 410008, China [7]General Hospital of PLA, Beijing 100853, China [8]The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China [9]Guizhou Provincial People’s Hospital, Guiyang 550002, China [10]Jiangxi Provincial Children’s Hospital, Nanchang 330006, China [11]Fourth Hospital of Hebei Medical University, Shijiazhuang 050019, China [12]Jiangsu Province Hospital, Nanjing 210029, China [13]Peking University People’s Hospital, Beijing 100044, China [14]The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China [15]Inner Mongolia People’s Hospital, Hohhot 010017, China [16]Heilongjiang Provincial Center for Disease Control and Prevention, Harbin 150030, China
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Healthcare-associated infections (HAIs) not only bring additional medical cost to the patients but also prolong the length of stay (LOS). 2119 HAI case-patients and 2119 matched control-patients were identified in 68 hospitals in 14 primary sampling provinces of 7 major regions of China. The HAI caused an increase in stay of 10.4 days. The LOS due to HAI increased from 9.7 to 10.9 days in different levels of hospitals. There was no statistically significant difference in the increased LOS between different hospital levels. The increased LOS due to HAI in different regions was 8.2 to 12.6 days. Comparing between regions, we found that the increased LOS due to HAI in South China is longer than other regions except the Northeast. The gastrointestinal infection (GI) caused the shortest extra LOS of 6.7 days while the BSI caused the longest extra LOS of 12.8 days. The increased LOS for GI was significantly shorter than that of other sites. Among 2119 case-patients, the non-multidrug-resistant pathogens were detected in 365 cases. The average increased LOS due to these bacterial infections was 12.2 days. E. coli infection caused significantly shorter LOS. The studied MDROs, namely, MRSA, VRE, ESBLs-E. coli, ESBLs-KP, CR-E. coli, CR-KP, CR-AB, and CR-PA were detected in 381 cases (18.0%). The average increased LOS due to these MDRO infections was 14 days. Comparing between different MDRO infections, we found that the increased LOS due to HAI caused by CR-PA (26.5 days) is longer than other MDRO infections (shorter than 19.8 days).

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出版当年[2019]版:
大类 | 3 区 生物
小类 | 3 区 生物工程与应用微生物 4 区 医学:研究与实验
最新[2025]版:
大类 | 4 区 医学
小类 | 4 区 生物工程与应用微生物 4 区 医学:研究与实验
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出版当年[2019]版:
Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Q3 MEDICINE, RESEARCH & EXPERIMENTAL
最新[2024]版:
Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Q3 MEDICINE, RESEARCH & EXPERIMENTAL

影响因子: 最新[2024版] 最新五年平均 出版当年[2019版] 出版当年五年平均 出版前一年[2018版] 出版后一年[2020版]

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第一作者机构: [1]Peking University First Hospital, Beijing 100034, China
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