Objective: This study aims to investigate the apoptosis of human ovarian carcinoma induced by lighting emitting diode (LED)-activated MPPa. Methods: A special LED equipment and human ovarian carcinoma cell line COC1/DDP was subjected in the study. Apoptosis was determined 4 hours after LED-activated MPPa using fluorescent staining with Hoechst 33258. Results: In the control groups, the nuclei were stained a less bright blue and the color was homogeneous. After being irradiated by LED-activated MPPa for 4 h, the blue emission light was much bright than the control cells. Condensation of chromatin and nuclear fragmentations was found in many PDT-treated cells. Conclusion: LED-activated MPPa could effectively induce apoptosis of human ovarian carcinoma cells.
基金：
Hi-Tech Research and Development Program of China (863 Program)National High Technology Research and Development Program of China [2006AA02Z4F0]
语种：
外文
WOS：
第一作者：
第一作者机构：[1]Chongqing Univ Med Sci, Inst Ultrasound Imaging, Chongqing 400010, Peoples R China[2]Chongqing Univ Med Sci, Affiliated Hosp 1, Dept Rehabil Med, Chongqing 400016, Peoples R China
推荐引用方式(GB/T 7714)：
Tan Yong,Xu Chuanshan,Xia Xinshu,et al.Apoptosis of human ovarian carcinoma induced by LED-activated MPPa[J].PROCEEDINGS OF THE 1ST CONFERENCE OF THE ASIAN OCEANIA SOCIETY OF PHYSICAL AND REHABILITATION MEDICINE.2008,233-+.
APA：
Tan, Yong,Xu, Chuanshan,Xia, Xinshu,Bai, Dingqun,Yu, Heping&He, Yong.(2008).Apoptosis of human ovarian carcinoma induced by LED-activated MPPa.PROCEEDINGS OF THE 1ST CONFERENCE OF THE ASIAN OCEANIA SOCIETY OF PHYSICAL AND REHABILITATION MEDICINE,,
MLA：
Tan, Yong,et al."Apoptosis of human ovarian carcinoma induced by LED-activated MPPa".PROCEEDINGS OF THE 1ST CONFERENCE OF THE ASIAN OCEANIA SOCIETY OF PHYSICAL AND REHABILITATION MEDICINE .(2008):233-+
