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Association of the spectral features of heart period signal with SNP of NOS in the Chinese Han nationality population

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机构: [1]Chongqing Univ Med Sci, Affiliated Hosp 1, Dept Geriatr, Chongqing 400016, Peoples R China
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To explore association of the spectral features of heart period signal with SNPs at 5 sites of NOS gene in the subjects (male 89, female77, aged 62.40+/-2.5 yrs) by allele specific primer PCR technique. It was found that the IT allelic genotype of NOS2 C-1173T associated with the highest RPH and TT allelic genotype of NOS3 G894T associated with the highest APH in HPS spectral parameters. This suggests the SNPs of NOS2 C-1173T and NOS3 G894T may be the deep layer factors to result in the variability of RPS spectral parameters.

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第一作者机构: [1]Chongqing Univ Med Sci, Affiliated Hosp 1, Dept Geriatr, Chongqing 400016, Peoples R China
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