机构：[1]The Department of Respiratory Medicine,The Third Hospital of Hebei Medical University,Shijiazhuang 050051,China[2]The Department of Pathology,The Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,China医技科室病理科河北医科大学第四医院[3]The Department of Pathology,Hebei Medical University,Shijiazhnang 050017,China
Objective:To detect the expressions of FEZ1 and Survivin in small cell lung cancer (SCLC) and poorly differentiated squamous cell carcinoma (PDSCC),and to approach a theoretical basis for clinical diagnosis and treatment.Methods:Immunohistochemical and flow cytometry method were used to detect the expressions of FEZ1 and Survivin.Apoptosis ratio and cell proliferation index in normal lung tissue,SCLC and POSCC were analyzed.Results:The expressions of FEZ1 and Survivin were significantly different between SCLC and PDSCC (P＜0.05).The apoptosis ratio and proliferation index of normal lung tissue were lower than those of PDSCC and SCLC,with a significant difference (P＜0.05).Conclusion:The expressions of FEZ1 and Survivin are significantly different between SCLC and PDSCC,indicating that detecting the expressions of the two indexes may be helpful for clinical diagnosis.
基金：
the Key Technologies R&D Program of Hebei Province(02276103D-11)
语种：
外文
第一作者：
第一作者机构：[1]The Department of Respiratory Medicine,The Third Hospital of Hebei Medical University,Shijiazhuang 050051,China
通讯作者：
推荐引用方式(GB/T 7714)：
Gang Chen,XiaolingWang,Yueping Liu,et al.FEZ1、Survivin在肺小细胞癌及低分化鳞状细胞癌蛋白表达及其在凋亡中的作用[J].CHINESE-GERMAN JOURNAL OF CLINICAL ONCOLOGY.2008,7(4):207-209.
APA：
Gang Chen,XiaolingWang,Yueping Liu,Lining Wang,Huichai Yang&Huijun Duan.(2008).FEZ1、Survivin在肺小细胞癌及低分化鳞状细胞癌蛋白表达及其在凋亡中的作用.CHINESE-GERMAN JOURNAL OF CLINICAL ONCOLOGY,7,(4)
MLA：
Gang Chen,et al."FEZ1、Survivin在肺小细胞癌及低分化鳞状细胞癌蛋白表达及其在凋亡中的作用".CHINESE-GERMAN JOURNAL OF CLINICAL ONCOLOGY 7..4(2008):207-209
