机构：[1]Research Center and Tumor Research Institute,the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China河北医科大学第四医院[2]The Third Department of Surgery, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China临床科室外三科河北医科大学第四医院
Circular RNA (circRNA), as a cluster of endogenous non-coding RNA (ncRNA) with tissue-specific expression in various eukaryotic species, may be involved in a variety of human physiological and pathological processes. With the continuous development of high-throughput sequencing in recent years, circRNA has been increasingly widely studied and become a hot spot in the field of tumor research. The immune system plays a crucial and complex role in tumor development. It is not only capable of inhibiting tumor progression, but it can also create conditions suitable for tumor development, thereby promoting tumor progression. Moreover, through ncRNA, tumor immunotherapy, as an essential means of tumor therapy, may regulate tumor immunity to achieve the purpose of treatment. This article reviews the role of circRNA in tumor immunity to supply a sufficient theoretical basis for tumor immunotherapy.
基金：
This work was supported by the National Nature Science Foundation of China (No. 81972722).
第一作者机构：[1]Research Center and Tumor Research Institute,the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China
共同第一作者：
通讯作者：
通讯机构：[1]Research Center and Tumor Research Institute,the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China[*1]Research Center and Tumor Research Institute, the Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China.
推荐引用方式(GB/T 7714)：
Meng Lingjiao,Ding Pingan,Liu Sihua,et al.The emerging prospects of circular RNA in tumor immunity[J].ANNALS OF TRANSLATIONAL MEDICINE.2020,8(17):doi:10.21037/atm-19-4751.
APA：
Meng, Lingjiao,Ding, Pingan,Liu, Sihua,Li, Ziyi,Sang, Meixiang&Shan, Baoen.(2020).The emerging prospects of circular RNA in tumor immunity.ANNALS OF TRANSLATIONAL MEDICINE,8,(17)
MLA：
Meng, Lingjiao,et al."The emerging prospects of circular RNA in tumor immunity".ANNALS OF TRANSLATIONAL MEDICINE 8..17(2020)
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