机构：[1]CellTherapy Laboratory,The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China[2]Department of Immunology, Basic Medical College, Hebei Medical University, Shijiazhuang, Hebei 050017, China[3]Department of Paediatrics, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China[4]Department of General Surgery,The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China[5]Department of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China[6]Department of Cardiac Surgery,The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China[7]School of Nursing, Hebei Medical University, Shijiazhuang, Hebei, China[8]Department of Breast Center,The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, China河北医科大学第四医院
Parkinson's disease (PD) is a type of degenerative disorder of the basal ganglia, causing tremor at rest, muscle rigidity hypokinesia, and dementia. The effectiveness of drug treatments gradually diminishes because the conversion to dopamine within the brain is increasingly disrupted by the progressive degeneration of the dopaminergic terminals. After long-term treatment, most patients with PD suffer from disability that cannot be satisfactorily controlled. To solve these issues, stem cells have recently been used for cell therapy of PD. In this review, the characteristics of different stem cells and their therapeutic effects on PD treatment will be discussed.
基金：
This work was supported by Grants from Hebei Province
Scientific and Technological Project (no. 12276102D), Hebei
Province International Scientific and Technological Cooperation
Project (nos. 10396106D and 13397703D), and the
Major Basic Research Program of Hebei Province (no.
14967719D).
语种：
外文
被引次数：
WOS：
PubmedID：
中科院分区：
出版当年[2016]版：
大类|3 区生物
小类|3 区生物工程与应用微生物4 区医学：研究与实验
最新[2025]版：
大类|4 区医学
小类|4 区生物工程与应用微生物4 区医学：研究与实验
JCR分区：
出版当年[2016]版：
Q2BIOTECHNOLOGY & APPLIED MICROBIOLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
最新[2024]版：
Q3BIOTECHNOLOGY & APPLIED MICROBIOLOGYQ3MEDICINE, RESEARCH & EXPERIMENTAL
第一作者机构：[1]CellTherapy Laboratory,The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China
通讯作者：
通讯机构：[1]CellTherapy Laboratory,The First Hospital of Hebei Medical University, Shijiazhuang, Hebei 050031, China[2]Department of Immunology, Basic Medical College, Hebei Medical University, Shijiazhuang, Hebei 050017, China
推荐引用方式(GB/T 7714)：
Zhang Jun,Wang Xianyun,Li Jing,et al.The Preclinical Research Progress of Stem Cells Therapy in Parkinson's Disease[J].BIOMED RESEARCH INTERNATIONAL.2016,2016:doi:10.1155/2016/5683097.
APA：
Zhang, Jun,Wang, Xianyun,Li, Jing,Huang, Rui,Yu, Xuerui...&Yan, Baoyong.(2016).The Preclinical Research Progress of Stem Cells Therapy in Parkinson's Disease.BIOMED RESEARCH INTERNATIONAL,2016,
MLA：
Zhang, Jun,et al."The Preclinical Research Progress of Stem Cells Therapy in Parkinson's Disease".BIOMED RESEARCH INTERNATIONAL 2016.(2016)
