SET8, a member of the SET domain-containing methyltransferase, has been implicated in various biological processes. In this study, SET8 was immunostained in 100 samples of gastric cancer tissues and semi-quantified using the HSCORE method to determine the predictive value of SET8 expression levels for gastric cancer outcome. The relationship between SET8 expression and the 5-year survival rate of gastric cancer patients was assessed. High expression of SET8 was associated with a shorter survival time in gastric cancer patients, and the level of SET8 expression was found to be an independent predictor of gastric cancer outcome (relative risk = 1.939; 95% confidence interval = 1.025-3.668; P = 0.042). Analysis of SET8 levels may help in the identification of patient subgroups that are at high risk for poor disease outcomes.
第一作者机构：[1]Hebei Med Univ, Hosp 4, Dept Pain Med & Rehabil, Shijiazhuang, Peoples R China
通讯作者：
通讯机构：[4]Hebei Med Univ, Hosp 4, Dept Radiol, Shijiazhuang, Peoples R China
推荐引用方式(GB/T 7714)：
Shi X. L.,Guo Z. J.,Wang X. L.,et al.SET8 expression is associated with overall survival in gastric cancer[J].GENETICS AND MOLECULAR RESEARCH.2015,14(4):15609-15615.doi:10.4238/2015.December.1.12.
APA：
Shi, X. L.,Guo, Z. J.,Wang, X. L.,Liu, X. L.&Shi, G. F..(2015).SET8 expression is associated with overall survival in gastric cancer.GENETICS AND MOLECULAR RESEARCH,14,(4)
MLA：
Shi, X. L.,et al."SET8 expression is associated with overall survival in gastric cancer".GENETICS AND MOLECULAR RESEARCH 14..4(2015):15609-15615
