机构:[1]Department of Radiation Oncology, Hebei Medical University Fourth Hospital, Shijiazhuang, People’s Republic of China河北医科大学第四医院[2]Department of Oncology, North China Petroleum Bureau General Hospital of Hebei Medical University, Renqiu, Hebei Province, People’s Republic of China
Icotinib hydrochloride is an orally administered small-molecule reversible tyrosine kinase inhibitor that has been independently researched and developed and has independent intellectual property rights in the People's Republic of China. Clinical trials have demonstrated that the response to icotinib among advanced non-small-cell lung cancer (NSCLC) patients who received at least one platinum-based chemotherapy regimen was not inferior to gefitinib. Since being launched August 2011 in the People's Republic of China, icotinib has been widely used in clinics, and has become an important treatment option for Chinese patients with advanced NSCLC. The present study presents the Phase I, II, and III clinical trials of icotinib and discusses current clinical applications in the People's Republic of China and future research directions.
第一作者机构:[1]Department of Radiation Oncology, Hebei Medical University Fourth Hospital, Shijiazhuang, People’s Republic of China
通讯作者:
通讯机构:[2]Department of Oncology, North China Petroleum Bureau General Hospital of Hebei Medical University, Renqiu, Hebei Province, People’s Republic of China[*1]Department of Oncology, North China Petroleum Bureau General Hospital of Hebei Medical University, 8 Huizhan Avenue, Renqiu, Hebei Province 062552, People’s Republic of China
推荐引用方式(GB/T 7714):
Liang Jun-Li,Ren Xiao-Cang,Lin Qiang.Treating advanced non-small-cell lung cancer in Chinese patients: focus on icotinib[J].ONCOTARGETS AND THERAPY.2014,7:761-769.doi:10.2147/OTT.S49233.
APA:
Liang, Jun-Li,Ren, Xiao-Cang&Lin, Qiang.(2014).Treating advanced non-small-cell lung cancer in Chinese patients: focus on icotinib.ONCOTARGETS AND THERAPY,7,
MLA:
Liang, Jun-Li,et al."Treating advanced non-small-cell lung cancer in Chinese patients: focus on icotinib".ONCOTARGETS AND THERAPY 7.(2014):761-769