机构:[1]Department of Obstetrics and Gynecology, Bethune International Peace Hospital, Shijiazhuang, Hebei, People’s Republic of China[2]Tumor Research Institute, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China河北医科大学第四医院[3]Department of Regenerative Medicine, Graduate School of Medicine and Pharmaceutical Science, University of Toyama, Sugitani, Toyama, Japan
Ovarian cancer is a leading cause of death among gynecologic malignancies. In this study, we reported the expression of melanoma-associated antigens A (MAGE-A) genes in peripheral blood from 80 patients with ovarian cancer and 30 healthy donors. MAGE-As expression was associated with the factors indicating poor prognosis. The expressions of MAGE-As and each individual MAGE-A genes were also associated with low overall survival of patients with ovarian cancer. Our results suggested MAGE-A genes may have the potential to be surveillance markers for the detection of circulating tumor cells and represent a poor prognosis for patients with ovarian cancer.
基金:
National Nature Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81001178]
第一作者机构:[1]Department of Obstetrics and Gynecology, Bethune International Peace Hospital, Shijiazhuang, Hebei, People’s Republic of China[2]Tumor Research Institute, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China
通讯作者:
通讯机构:[1]Department of Obstetrics and Gynecology, Bethune International Peace Hospital, Shijiazhuang, Hebei, People’s Republic of China[*1]Department of Obstetrics and Gynecology, Bethune International Peace Hospital, Shijiazhuang, Hebei 050082, People’s Republic of China
推荐引用方式(GB/T 7714):
Sang Meixiang,Wu Xiaohua,Fan Xiaojie,et al.Multiple MAGE-A genes as surveillance marker for the detection of circulating tumor cells in patients with ovarian cancer[J].BIOMARKERS.2014,19(1):34-42.doi:10.3109/1354750X.2013.865275.
APA:
Sang, Meixiang,Wu, Xiaohua,Fan, Xiaojie,Sang, Meijie,Zhou, Xinliang&Zhou, Nan.(2014).Multiple MAGE-A genes as surveillance marker for the detection of circulating tumor cells in patients with ovarian cancer.BIOMARKERS,19,(1)
MLA:
Sang, Meixiang,et al."Multiple MAGE-A genes as surveillance marker for the detection of circulating tumor cells in patients with ovarian cancer".BIOMARKERS 19..1(2014):34-42