机构：[1]Tumor Research Institute, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, People’s Republic of China河北医科大学第四医院[2]Research Center, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, People’s Republic of China河北医科大学第四医院
The melonoma-associated antigens family A (MACE-A) belongs to cancer/testis antigens (CTA) that are expressed in a wide variety of malignant tumors but not in normal adult tissues except for testis. Interestingly, germ cells do not express MHC class I antigen, implying that these gene products should be ideal targets for cancer immunotherapy. The strict tumor-specific expression of MACE-As has led to several immunotherapeutic trials targeting some of these proteins. In this review, we briefly described the expression and activation mechanism of MACE-As in cancer. We also summarized the biological functions of MACE-As in cell progress and the progress of the cancer immunotherapy targeting MACE-A family. (C) 2011 Elsevier Ltd. All rights reserved.
基金：
National Nature Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81001178]
第一作者机构：[1]Tumor Research Institute, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, People’s Republic of China[2]Research Center, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, People’s Republic of China
共同第一作者：
通讯作者：
通讯机构：[1]Tumor Research Institute, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, People’s Republic of China[2]Research Center, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, People’s Republic of China[*1]Research Center, the Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050017, People’s Republic of China.
推荐引用方式(GB/T 7714)：
Sang Meixiang,Lian Yishui,Zhou Xinliang,et al.MAGE-A family: Attractive targets for cancer immunotherapy[J].VACCINE.2011,29(47):8496-8500.doi:10.1016/j.vaccine.2011.09.014.
APA：
Sang, Meixiang,Lian, Yishui,Zhou, Xinliang&Shan, Baoen.(2011).MAGE-A family: Attractive targets for cancer immunotherapy.VACCINE,29,(47)
MLA：
Sang, Meixiang,et al."MAGE-A family: Attractive targets for cancer immunotherapy".VACCINE 29..47(2011):8496-8500
医学