机构：[1]Department of Anesthesiology, Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang,临床科室麻醉科河北医科大学第四医院[2]Department of Biomedical Engineering, School of Medicine, Tsinghua University,[3]Neuroscience Research Institute and Department of Neurobiology, Peking University[4]Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China
It has been proposed that high-frequency oscillations (HFOs) and underlying conventional somatosensory-evoked potentials (SEPs) have different brain origins. To further explore the neural mechanism of HFOs, we recorded the SEPs responding to high-intensity electrical stimulation applied to the hind paw of conscious, freely moving rats. We also investigated the effect of systemic morphine on HFOs and the conventional SEPs. HFOs after high-intensity electrical stimulation showed a widespread distribution in frontal and temporal regions of the brain. The amplitude of HFOs was significantly decreased by systemic morphine, whereas the primary conventional SEP components remained unaffected. The different changes in HFOs and primary SEP components after systemic morphine administration provided further evidence for the hypothesis that HFOs and underlying conventional SEP components have different origins. NeuroReport 21:2-7 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.
基金：
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [30570577, 30770688]
第一作者机构：[1]Department of Anesthesiology, Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang,
共同第一作者：
通讯作者：
通讯机构：[3]Neuroscience Research Institute and Department of Neurobiology, Peking University[4]Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China[*1]Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, 10A Datun Road, Chaoyang District, Beijing 100101, China
推荐引用方式(GB/T 7714)：
Li Guo-Liang,Qiao Zhi-Mei,Han Ji-Sheng,et al.Dissociated behavior of low-frequency responses and high-frequency oscillations after systemic morphine administration in conscious rats[J].NEUROREPORT.2010,21(1):2-7.doi:10.1097/WNR.0b013e32832e0c5a.
APA：
Li, Guo-Liang,Qiao, Zhi-Mei,Han, Ji-Sheng&Luo, Fei.(2010).Dissociated behavior of low-frequency responses and high-frequency oscillations after systemic morphine administration in conscious rats.NEUROREPORT,21,(1)
MLA：
Li, Guo-Liang,et al."Dissociated behavior of low-frequency responses and high-frequency oscillations after systemic morphine administration in conscious rats".NEUROREPORT 21..1(2010):2-7
