详情页

当前位置：首页 > 详情页

A new taxane composed of two N-formyl rotamers from Taxus canadensis

文献详情

资源类型：

WOS体系：

收录情况： ◇ SCIE

作者：

机构： [1]Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, 050017 Shijiazhuang, Hebei Province, PR China [2]Department of Radiation Oncology, The Fourth Affiliated Hospital, Hebei Medical University, 050010 Shijiazhuang, Hebei Province, PR China [3]Department of Chemistry, Queen’s University, Kingston, Ontario, Canada K7L 3N6 [4]Syngenta Jealott’s Hill International Research Centre, Bracknell, Berkshire RG42 6EY, United Kingdom [5]Department of Applied Bioorganic Chemistry, Division of Bioscience and Biotechnology for Future Bioindustry, Graduate School of Agricultural Sciences, Tohoku University, 1-1 Tsutsumidori-Amamiya, Aoba-ku, Sendai 981-8555, Japan

出处：

DOI：

ISSN：

摘要：

A taxane with an amino-side chain on C-5 was identified for the first time from rooted cuttings of the Canadian yew, Taxus camadensis. The structure was characterized as 7 beta,9 alpha,10 beta,13 alpha-tetraacetoxy-5 alpha-[3'-(N-formyl-N-methylamino)-3'-phenylpropanoyl]oxytaxa-4(20),12-diene (1) on the basis of 1D-, 2D-NMR data, and HR-FABMS analyses. The spectra revealed that in CDCl(3) solution 1 was composed of two rotamers (1a and 1b) in a ratio of approximately 2:1. (C) 2008 Elsevier Ltd. All rights reserved.

基金：

语种：

被引次数：

WOS：

中科院分区：

出版当年[2008]版：

大类 | 3 区化学

小类 | 3 区有机化学

最新[2025]版：

大类 | 4 区化学

小类 | 4 区有机化学

JCR分区：

出版当年[2008]版：

Q2 CHEMISTRY, ORGANIC

最新[2024]版：

Q3 CHEMISTRY, ORGANIC

影响因子： 1.5 最新[2024版] 1.5 最新五年平均 2.538 出版当年[2008版] 2.382 出版当年五年平均 2.615 出版前一年[2007版] 2.66 出版后一年[2009版]

第一作者：

第一作者机构： [1]Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, 050017 Shijiazhuang, Hebei Province, PR China

通讯作者：

推荐引用方式(GB/T 7714)：

APA：

MLA：