A Study Evaluating the Efficacy and Safety of Adjuvant Giredestrant Compared With Physician's Choice of Adjuvant Endocrine Monotherapy in Participants With Estrogen Receptor-Positive, HER2-Negative Early Breast Cancer (lidERA Breast Cancer)
研究单位：[1]Hoffmann-La Roche[2]Southern Cancer Center,Daphne,Alabama,United States,36526[3]CBCC Global Research Inc., at Comprehensive Blood and Cancer Center,Bakersfield,California,United States,93309[4]Arrowhead Regional Medical Center,Colton,California,United States,92324[5]Cancer and Blood Specialty Clinic,Fountain Valley,California,United States,92708[6]Long Beach Memorial Medical Center,Fountain Valley,California,United States,92708[7]USC Norris Cancer Center,Los Angeles,California,United States,90033[8]The Center for Cancer Prevention and Treatment at St.Joseph Hospital of Orange,Orange,California,United States,92868[9]Stanford University Medical Center,Palo Alto,California,United States,94304[10]Kaiser Permanente - Roseville,Roseville,California,United States,95661[11]Kaiser Permanente - San Diego,San Diego,California,United States,92120[12]Kaiser Permanente - San Francisco (2238 Geary),San Francisco,California,United States,94115[13]Stanford Cancer Center South Bay,San Jose,California,United States,95124[14]Sansum Clinic,Santa Barbara,California,United States,93105[15]Kaiser Permanente - Santa Clara,Santa Clara,California,United States,95051[16]UCLA Hematology/Oncology,Santa Monica,California,United States,90404[17]St Joseph Heritage Healthcare,Santa Rosa,California,United States,95403[18]Torrance Memorial Physician Network/Cancer Care,Torrance,California,United States,90505[19]Kaiser Permanente - Vallejo,Vallejo,California,United States,94589[20]Valley Breast Care and Women's Health Center,Van Nuys,California,United States,91405[21]Banner MD Anderson Cancer Center,Greeley,Colorado,United States,85234[22]Rocky Mountain Cancer Centers (Longmont) - USOR,Longmont,Colorado,United States,80501[23]Stamford Hospital[24]Clincal Trials Office - 1st Fl - Bennett Cancer Cente,Stamford,Connecticut,United States,06902[25]University of Florida[26]UF Health Shands Cancer Hospital,Gainesville,Florida,United States,32608[27]Memorial Healthcare System - Memorial Regional Hospital,Hollywood,Florida,United States,33021[28]Baptist - MD Anderson Cancer Center,Jacksonville,Florida,United States,32207[29]Mount Sinai Comprehensive Cancer Center,Miami Beach,Florida,United States,33140[30]Miami Cancer Institute of Baptist Health, Inc.,Miami,Florida,United States,33176[31]Orlando Health Cancer Institute,Orlando,Florida,United States,32806[32]Miami Cancer Institute-Plantation,Plantation,Florida,United States,33324[33]Memorial Health University Cancer Center,Savannah,Georgia,United States,31404[34]University of Illinois at Chicago,Chicago,Illinois,United States,60612[35]University of Chicago Hospital,Chicago,Illinois,United States,60637[36]Elmhurst Cancer Center,Elmhurst,Illinois,United States,60126[37]Joliet Oncology Hematology Associates, Ltd.,Joliet,Illinois,United States,60435[38]Edward Cancer Center Naperville,Naperville,Illinois,United States,60540[39]Edward Cancer Center Plainfield,Plainfield,Illinois,United States,60585[40]Oncology Associates at Mercy Medical Center,Cedar Rapids,Iowa,United States,52403[41]University of Iowa,Iowa City,Iowa,United States,52242-1086[42]Cancer Center of Kansas - Kingman,Kingman,Kansas,United States,67068[43]Lahey Clinic Med Ctr,Lexington,Kentucky,United States,02421[44]University of Kentucky[45]Markey Cancer Center,Lexington,Kentucky,United States,40536[46]Norton Cancer Institute - MDC,Louisville,Kentucky,United States,40202[47]Hematology/Oncology Clinic, LLP,Baton Rouge,Louisiana,United States,70809[48]University Medical Center New Orleans,New Orleans,Louisiana,United States,70112[49]UPMC Western Maryland - Schwab Family Cancer Center,Cumberland,Maryland,United States,21502[50]University of Maryland[51]St. Joseph Medical Center,Towson,Maryland,United States,21204[52]Massachusetts General Hospital[53]Lurie Center for Autism,Lexington,Massachusetts,United States,02421[54]Universi
研究目的：
This is a Phase III, global, randomized, open-label, multicenter, study evaluating the efficacy and safety of adjuvant giredestrant compared with endocrine therapy of physician's choice in participants with medium- and high-risk Stage I-III histologically confirmed estrogen receptor (ER)-positive and human epidermal growth factor receptor 2 (HER2)-negative early breast cancer.
