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Regorafenib Treatment Patterns and Survival Outcomes in Advanced Colorectal Cancer: A Real-world Study

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研究单位： [1]Cancer Institute and Hospital, Chinese Academy of Medical Sciences [2]Jiangsu Cancer Institute & Hospital [3]The Affiliated Hospital of Qingdao University [4]Shanxi Province Cancer Hospital [5]Affiliated Hospital of Hebei University [6]Shandong Cancer Hospital and Institute [7]The First Affiliated Hospital of Zhengzhou University [8]Hebei Medical University Fourth Hospital [9]First Hospital of China Medical University [10]Beijing Hospital

研究目的：

This is a multi-center, retrospective, real-world study. The purpose of this study is to observe the effectiveness and safety of regorafenib in Chinese advanced colorectal cancer patients. The main observational goals include overall survival(OS), 6 month OS rate, 1 year OS rate, and treatment time failure (TTF), other study goals include objective response rate( ORR)、Disease control rate（DCR）and adverse event(AE) of regorafenib.