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Focus on oliguria during renal replacement therapy

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机构: [1]Department of Intensive Care Unit (ICU), The Afliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, People’s Republic of China [2]Department of Intensive Care Unit (ICU), Peking Union Medical College Hospital, Beijing 100005, People’s Republic of China [3]Department of Intensive Care Unit (ICU), The First Afliated Hospital of Tsinghua University, Beijing 100016, People’s Republic of China [4]Department of Intensive Care Unit (ICU), The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050011, People’s Republic of China
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关键词: Oliguria  Renal replacement therapy  Renal oxygen delivery  Renal oxygen consumption  Acute kidney injury

摘要:
Oliguria is a clinical symptom characterized by decreased urine output, which can occur at any stage of acute kidney injury and also during renal replacement therapy. In some cases, oliguria may resolve with adjustment of blood purification dose or fluid management, while in others, it may suggest a need for further evaluation and intervention. It is important to determine the underlying cause of oliguria during renal replacement therapy and to develop an appropriate treatment plan. This review looks into the mechanisms of urine production to investigate the mechanism of oliguria during renal replacement therapy from two aspects: diminished glomerular filtration rate and tubular abnormalities. The above conditions all implying a renal oxygen supply-demand imbalance, which is the signal of worsening kidney injury. It also proposes a viable clinical pathway for the treatment and management of patients with acute kidney injury receiving renal replacement therapy.© 2024. The Author(s).

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出版当年[2025]版:
大类 | 3 区 医学
小类 | 3 区 麻醉学
最新[2025]版:
大类 | 3 区 医学
小类 | 3 区 麻醉学
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出版当年[2024]版:
Q2 ANESTHESIOLOGY
最新[2024]版:
Q2 ANESTHESIOLOGY

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第一作者机构: [1]Department of Intensive Care Unit (ICU), The Afliated Hospital of Guizhou Medical University, Guiyang, Guizhou 550004, People’s Republic of China
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通讯机构: [4]Department of Intensive Care Unit (ICU), The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050011, People’s Republic of China
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