Tumor-associated macrophages (TAMs) play an important role in promoting cancer in the breast cancer microenvironment. A large number of preclinical studies have demonstrated that TAMs regulate related signaling pathways by releasing a variety of chemokines, affecting breast cancer growth, metastasis, and drug resistance. In recent years, TAMs have attracted much attention as potential biomarkers for breast cancer. This article reviews the preclinical evidence of the relationship between TAMs and the breast cancer microenvironment, the role of TAMs in prognosis, and the clinical outcomes related to targeted therapy.
第一作者机构:[1]Hebei Medical University, Fourth Affiliated Hospital, Hebei Province Tumor Hospital, China
通讯作者:
通讯机构:[1]Hebei Medical University, Fourth Affiliated Hospital, Hebei Province Tumor Hospital, China
推荐引用方式(GB/T 7714):
Lu Jing,Ma Li.The role of tumor-associated macrophages in the development, metastasis and treatment of breast cancer[J].PATHOLOGY RESEARCH AND PRACTICE.2020,216(9):doi:10.1016/j.prp.2020.153085.
APA:
Lu, Jing&Ma, Li.(2020).The role of tumor-associated macrophages in the development, metastasis and treatment of breast cancer.PATHOLOGY RESEARCH AND PRACTICE,216,(9)
MLA:
Lu, Jing,et al."The role of tumor-associated macrophages in the development, metastasis and treatment of breast cancer".PATHOLOGY RESEARCH AND PRACTICE 216..9(2020)