详情页

当前位置：首页 > 详情页

A Mixed-ligand Zn(II)-based Coordination Polymer for Selectively Detect 2,4,6-Trinitrophenol (TNP) and Treatment Effect on Periodontal Diseases via Inhibition Effect on P. gingivalis Growth

6| 导出 | 链接全文 |

文献详情

资源类型：

WOS体系：

Pubmed体系：

收录情况： ◇ SCIE ◇ EI

作者：

机构： [1]Department of Stomatology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, CHINA [2]Department of Stomatology, The Second Hospital of Shijiazhuang, Shijiazhuang, Hebei, CHINA [3]Department of Stomatology, China General Hospital, Ningbo, Zhejiang, CHINA

出处：

DOI：

ISSN：

关键词： Zn(II)-complex mixed-ligand TNP sensing periodontal diseases molecular docking

摘要：

A new difunctional Zn(II) coordination polymer (CP) with the chemical formula of [Zn(TBTA) (L)(1.5)](n) (1) has been synthesized hydrothermally from tetrabromoterephthalic acid (H(2)TBTA) and 4,4'-bis(imidazole-1-yl)-biphenyl (L) ligands. Furthermore, due to its strong intense emission and open N donor sites, complex 1 could be used as a light-emitting sensor to determine 2,4,6-trinitrophenol (TNP) which has high selectivity and sensitivity. Furthermore, the anti-bacterial effect of the compound against P. gingivalis in vitro was evaluated by measuring the P. gingivalis growth curves after compound treatment. And the RT-PCR assay was performed to detect the relative expression of ragA and ragB, which are important for the P. gingivalis growth. The potential anti-infectious mechanism was further studied by using molecular docking technique.

语种：

被引次数：

WOS：

PubmedID：

中科院分区：

出版当年[2020]版：

大类 | 4 区工程技术

小类 | 4 区应用化学 4 区食品科技

最新[2025]版：

大类 | 4 区农林科学

小类 | 4 区应用化学 4 区食品科技

JCR分区：

出版当年[2020]版：

Q3 CHEMISTRY, APPLIED Q4 FOOD SCIENCE & TECHNOLOGY

最新[2024]版：

Q3 CHEMISTRY, APPLIED Q3 FOOD SCIENCE & TECHNOLOGY

影响因子： 1.8 最新[2024版] 2 最新五年平均 1.601 出版当年[2020版] 1.768 出版当年五年平均 1.304 出版前一年[2019版] 1.628 出版后一年[2021版]

第一作者：

第一作者机构： [1]Department of Stomatology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei, CHINA

通讯作者：

通讯机构： [2]Department of Stomatology, The Second Hospital of Shijiazhuang, Shijiazhuang, Hebei, CHINA [*1]Department of Stomatology, The Second Hospital of Shijiazhuang, Shijiazhuang, Hebei, CHINA

推荐引用方式(GB/T 7714)：

APA：

MLA：

相关文献

[1]Mechanism of Astragalus membranaceus in the treatment of laryngeal cancer based on gene co-expression network and molecular docking [2]Integrated network pharmacology, molecular docking, and animal experiments to reveal the potential mechanism of hesperetin on COPD [3]Antibacterial mechanism of action and in silico molecular docking studies of Cupressus funebris essential oil against drug resistant bacterial strains [4]Two Cu(II) and Co(II)-based coordination polymers based on the N,S-mixed donor ligand: structural characterization and anti-endometrial cancer activity [5]Molecular docking and in vitro experiments verified that kaempferol induced apoptosis and inhibited human HepG2 cell proliferation by targeting BAX, CDK1, and JUN [6]Effect and Mechanisms of Huangqi-Shanzhuyu in the Treatment of Diabetic Nephropathy based on Network Pharmacology and In Vitro Experiments [7]Three new Cd(II)/Zn(II) coordination polymers assembled via dual-ligand strategy: crystal structures and luminescent properties [8]基于网络药理学和分子对接技术探讨中药外敷1号应用于唇炎的相关机制 [9]Determining novel candidate anti-hepatocellular carcinoma drugs using interaction networks and molecular docking between drug targets and natural compounds of SiNiSan. [10]基于网络药理学和分子对接研究化湿行瘀清热方治疗口腔扁平苔藓的作用机制