Introduction: Pancreatic cancer is a type of high-grade malignant tumor of digestive tract, which is difficult to diagnose and treat. The obstructive jaundice induced by pancreatic cancer may lead to hepatic failure and accelerated progress of disease. On this basis, percutaneous transhepaticcholangial drainage (PTCD) and biliary tract external drainage (BTED) can relieve the symptoms of obstructive jaundice induced by pancreatic cancer, and improve patients' disease condition their quality of life. Materials and method: In this research, the selected pancreatic cancer patient (who had been misdiagnosed to take gall-bladder. jejunum side to side anastomosis + jejuntan-jejuntan side to side anastomosis internal drainage rather than take pancreaticoduodenectomy, and refused to take surgical treatment again) suffered the complication of obstructive jaundice andserious infection. interventional therapies with PTCD and BTED were performed to relieve the symptoms of obstructive jaundice and control the infection. Results: Through implementing interventional treatment of complications of pancreatic cancer, patients' life quality was improved and their life time was prolonged. Discussion:We believe interventional therapy is a safe and effective Conservative treatment through this case study.