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Selected updates in molecular and genomic pathology of esophageal cancer.

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收录情况： ◇ SCIE

作者：

机构： [1]Department of Pathology, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, Shijiazhuang, China. [2]Department of Pathology, Brigham and Women’s Hospital and Harvard Medical School, Boston, Massachusetts. [3]Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. [4]Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China

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关键词： esophageal cancer HER2 PD-1/PD-L1 human papillomavirus molecular genomic

摘要：

Recent years have seen rapid advances in the field of molecular and genomic pathology that have not only improved understanding of esophageal carcinogenesis and tumor immune environment in general but also have reshaped pathology practice and clinical management. In this article, we provide updates on three topics (1) human epidermal growth factor receptor 2, the first and most important biomarker in targeted therapy of esophageal cancer; (2) programmed death 1/programmed death ligand 1, recent biomarkers that have shown promise in treating both esophageal adenocarcinoma and esophageal squamous cell carcinoma; and (3) human papillomavirus involvement in esophageal carcinogenesis, one of the most debated topics in the field, discussed here with a renewed understanding from recent genomic and molecular data. © 2020 New York Academy of Sciences.

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出版当年[2020]版：

大类 | 2 区综合性期刊

小类 | 2 区综合性期刊

最新[2025]版：

大类 | 2 区综合性期刊

小类 | 2 区综合性期刊

JCR分区：

出版当年[2020]版：

Q1 MULTIDISCIPLINARY SCIENCES

最新[2023]版：

Q1 MULTIDISCIPLINARY SCIENCES

影响因子： 4.1 最新[2023版] 6.3 最新五年平均 5.691 出版当年[2020版] 6.3 出版当年五年平均 4.728 出版前一年[2019版] 6.499 出版后一年[2021版]

第一作者：

第一作者机构： [1]Department of Pathology, Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital, Shijiazhuang, China.

通讯作者：

通讯机构： [4]Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China [*1]Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai 200032, P.R. China.

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Selected updates in molecular and genomic pathology of esophageal cancer.

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