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Gender differences in colorectal cancer survival: A meta-analysis

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机构: [1]Department of General Surgery, Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China [2]Animal Center, Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China [3]Department of Radiotherapy, Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, 050010, China
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关键词: colorectal cancer gender overall survival cancer-specific survival OS CSS meta-analysis

摘要:
A meta-analysis was conducted to determine the influence of gender on overall survival (OS) and cancer-specific survival (CSS) in colorectal cancer patients. Major databases were searched for clinical trials, which compare survival differences between male and female for colorectal cancer patients. A list of these studies and references, published in English and Chinese from 1960 to 2017, was obtained independently by two reviewers from databases such as PubMed, Medline, ScienceDirect, the China National Knowledge Infrastructure (CNKI) and Web of Science. Overall survival and cancer-specific survival were compared using Review Manager 5.3. Females had significantly better OS (hazard ratio [HR] = 0.87; 95% confidence interval [CI] = 0.85-0.89) and CSS (HR = 0.92; 95% CI = 0.89-0.95) than males after meta-analysis. These results suggest that gender seems to be a significant factor influencing survival results among colorectal cancer patients.

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出版当年[2017]版:
大类 | 2 区 医学
小类 | 2 区 肿瘤学
最新[2025]版:
大类 | 2 区 医学
小类 | 2 区 肿瘤学
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出版当年[2017]版:
Q1 ONCOLOGY
最新[2023]版:
Q1 ONCOLOGY

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第一作者机构: [1]Department of General Surgery, Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China
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通讯机构: [1]Department of General Surgery, Fourth Affiliated Hospital of Hebei Medical University, Shijiazhuang, China [*1]Department of General Surgery, Fourth Affiliated Hospital of Hebei Medical University, Health Road, No. 12, North Building Street, Qiaodong District, Shijiazhuang, China
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