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Millifolide A, a dimeric ether of degraded sesquiterpene lactones, inhibited the proliferation of human lung cancer cell line A549.

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机构: [1]Hebei Key Laboratory of Forensic Medicine, Collaborative Innovation Center of Forensic Medical Molecular Identification, College of Forensic Medicine, Hebei Medical University, Shijiazhuang, Hebei Province, P.R. China. [2]The Fourth Hospital of Hebei Medical University, Shijiazhuang, P.R. China. [3]Graduate School of Environmental and Life Science, Okayama University, Okayama, Japan.
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关键词: Achillea millefolium L millifolide A human lung cancer cells antiproliferation apoptosis

摘要:
The inhibitory effect of three degraded sesquiterpene lactones, iso-seco-tanapartholide, arteludooicinolide A and millifolide A isolated from Achillea millefolium L., on anti-human lung cancer cells was examined using MTT and reporter gene assays. Millifolide A has significant inhibitory effects on the proliferation of human lung cancer cells probably through inducing cell apoptosis.

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出版当年[2022]版:
大类 | 3 区 化学
小类 | 3 区 应用化学 4 区 药物化学
最新[2025]版:
大类 | 3 区 化学
小类 | 3 区 应用化学 4 区 药物化学
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出版当年[2022]版:
Q3 CHEMISTRY, APPLIED Q4 CHEMISTRY, MEDICINAL
最新[2023]版:
Q3 CHEMISTRY, APPLIED Q3 CHEMISTRY, MEDICINAL

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第一作者机构: [1]Hebei Key Laboratory of Forensic Medicine, Collaborative Innovation Center of Forensic Medical Molecular Identification, College of Forensic Medicine, Hebei Medical University, Shijiazhuang, Hebei Province, P.R. China.
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