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Cancer-Fighting Molecules-Taxol and its Analogs

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收录情况： ◇ SCIE

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机构： [1]Department of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine, 361 Zhongshan East Road, Shijiazhuang, 050017, Hebei Province, P. R. China [2]Department of Thoracic, Fourth Hospital of Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang, 050017, Hebei Province, P. R. China [3]Department of Medicinal Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang, 050017, Hebei Province, P. R. China

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关键词： Taxol taxol analogy taxane Taxus anti-cancer

摘要：

Natural products have not only yielded new and effective drugs but have also provided insight into new mechanisms of action. Paclitaxel (Taxol) as the first promoters of tubulin polymerization plays important roles in the war against cancer and in the exploring new microtubule-binding drugs. The present review summarized the development of paclitaxel and its analogues which can be used as the precurce of synthesis of Taxol and its analogues.

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出版当年[2012]版：

大类 | 3 区化学

小类 | 3 区有机化学

最新[2025]版

：

大类 | 4 区化学

小类 | 4 区有机化学

JCR分区：

出版当年[2012]版：

Q2 CHEMISTRY, ORGANIC

最新[2024]版：

Q3 CHEMISTRY, ORGANIC

影响因子： 2.1 最新[2024版] 2.3 最新五年平均 3.039 出版当年[2012版] 3.222 出版当年五年平均 3.064 出版前一年[2011版] 2.537 出版后一年[2013版]

第一作者：

第一作者机构： [1]Department of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine, 361 Zhongshan East Road, Shijiazhuang, 050017, Hebei Province, P. R. China

通讯作者：

通讯机构： [1]Department of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine, 361 Zhongshan East Road, Shijiazhuang, 050017, Hebei Province, P. R. China [3]Department of Medicinal Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, Shijiazhuang, 050017, Hebei Province, P. R. China [*1]Department of Forensic Medicine, Hebei Medical University, Hebei Key Laboratory of Forensic Medicine, 361 Zhongshan East Road, Shijiazhuang, 050017, Hebei Province, P. R. China

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